BDBM50151983 3-{4-[4-(2-Oxo-2H-chromen-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL189704

SMILES O=c1ccc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1

InChI Key InChIKey=JYRQRDDPHJEJCJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50151983   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50151983(3-{4-[4-(2-Oxo-2H-chromen-6-yl)-piperazin-1-yl]-bu...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of [3H]-5-HT re-uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed